Contrastive grammar : a theory and practice handbook

En consonancia con los lineamientos del programa vigente de Gramática Contrastiva, materia incluida en el programa de estudios del Traductorado de Inglés de la Facultad de Lenguas, Universidad Nacional de Córdoba, el objetivo principal de Contrastive Grammar: A Theory and Practice Handbook es brindar a los estudiantes un manual que combine las gramáticas descriptivas del inglés y del español. No pretende ser una revisión completa de todas las diferencias lingüísticas existentes entre ambas lenguas: por el contrario, el objetivo del presente manual es combinar información teórica clave con prácticas variadas respecto de estructuras dispares que representan la fuente más frecuente de interferencia entre los dos sistemas.Fil: Gómez Calvillo, M. Natalia. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Meehan, Patricia. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Díaz, M. Josefina. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Rolfi, Laura. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina

Grammar practice : theory and practice

Fil: Luque Colombres, María Candelaria. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Meehan, Patricia. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Oliva, María Belén. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Rius, Natalia. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: de Maussion, Ana. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Neyra, Vanina Pamela. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Our main objective when writing this handbook has been to design some kind of material that would provide the first-year university student at Facultad de Lenguas with the basic foundations of English grammar. Although this handout could be used as a self-study grammar guide, the student should bear in mind it is meant to be used as a complement of class work. Therefore, the material included in the present publication has not been organized according to the level of difficulty, but rather in accordance with the syllabus of the subject. Each chapter brings along graded exercises which have been carefully designed to improve and consolidate the grammar topics included in the syllabus of the subject. Finally, we would like to point out that to round off each unit, we have decided to include texts (often authentic ones) in an attempt to offer the student a new perspective on the subject: one which relates grammatical structure systematically to meaning and use.Fil: Luque Colombres, María Candelaria. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Meehan, Patricia. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Oliva, María Belén. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Rius, Natalia. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: de Maussion, Ana. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Neyra, Vanina Pamela. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina

Shell we cook it? An experimental approach to the microarchaeological record of shellfish roasting

In this paper, we investigate the microarchaeological traces and archaeological visibility of shellfish cooking activities through a series of experimental procedures with direct roasting using wood-fueled fires and controlled heating in a muffle furnace. An interdisciplinary geoarchacological approach, combining micromorphology, FTIR (in transmission and ATR collection modes), TGA and XRD, was used to establish a baseline on the mineralogical transformation of heated shells from aragonite to calcite and diagnostic sedimentary traces produced by roasting fire features. Our experimental design focused on three main types of roasting procedures: the construction of shallow depressions with heated rocks (pebble cuvette experiments), placing shellfish on top of hot embers and ashes (fire below experiment), and by kindling short-lived fires on top of shellfish (fire above experiments). Our results suggest that similar shellfish roasting procedures will largely create microstratigraphic signatures of anthropogenically reworked combusted material spatially "disconnected" from the actual combustion locus. The construction of shallow earth ovens might entail an increased archaeological visibility, and some diagnostic signatures of in situ hearths can be obtained by fire below roasting activities. We also show that macroscopic visual modifications and mineralogical characterization of discarded shellfish might be indicative of specific cooking activities versus secondary burning.Max Planck Societyinfo:eu-repo/semantics/publishedVersio

Minimal information for studies of extracellular vesicles 2018 (MISEV2018):a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles (“MISEV”) guidelines for the field in 2014. We now update these “MISEV2014” guidelines based on evolution of the collective knowledge in the last four years. An important point to consider is that ascribing a specific function to EVs in general, or to subtypes of EVs, requires reporting of specific information beyond mere description of function in a crude, potentially contaminated, and heterogeneous preparation. For example, claims that exosomes are endowed with exquisite and specific activities remain difficult to support experimentally, given our still limited knowledge of their specific molecular machineries of biogenesis and release, as compared with other biophysically similar EVs. The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities. Finally, a checklist is provided with summaries of key points

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

Clinical presentation of congenital heart disease is heterogeneous, making identification of the disease-causing genes and their genetic pathways and mechanisms of action challenging. By using in vivo electrocardiography, transthoracic echocardiography and microcomputed tomography imaging to screen 3,894 single-gene-null mouse lines for structural and functional cardiac abnormalities, here we identify 705 lines with cardiac arrhythmia, myocardial hypertrophy and/or ventricular dilation. Among these 705 genes, 486 have not been previously associated with cardiac dysfunction in humans, and some of them represent variants of unknown relevance (VUR). Mice with mutations in Casz1, Dnajc18, Pde4dip, Rnf38 or Tmem161b genes show developmental cardiac structural abnormalities, with their human orthologs being categorized as VUR. Using UK Biobank data, we validate the importance of the DNAJC18 gene for cardiac homeostasis by showing that its loss of function is associated with altered left ventricular systolic function. Our results identify hundreds of previously unappreciated genes with potential function in congenital heart disease and suggest causal function of five VUR in congenital heart disease